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. 2016 Nov 21;60(12):7115–7127. doi: 10.1128/AAC.01061-16

TABLE 3.

Nonsynonymous mutations in AR-12-resistant S. cerevisiae strains

Gene Chromosome/position Codon changea Amino acid change Presence of mutation in strain:
16-14 16-77 64-77
TRA1 VIII/304575 AAC-AAA N605K + + +
YPR137-C XVI/805261 GTC-ATG V1670 M + + +
YPR137-C XVI/805267 CAC-TAC H1668Y + + +
SVL3 XVI/489657 GGC-AGC G570S + +
YIL169C IX/25418 GAT-GGT D230G + +
PDR1 VII/469717 TCT-TAT S861Y + +
PDR1 VII/469849 ACA-AAA T817K +
KCC4 III/81761 AGT-AAT S867N +
WHI2 XV/411309 TCA-TAA S147Stop +
YLL066W-B VIII/5683 CCA-ACA P27T +
YRF1-6 VIII/5871 TTA-TCA L27S +
MMS2 VII/346902 ATG-ATT M1I +
HPF1 VIII/31103 GAA-GCA E169A +
a

Nucleotide changes are indicated by underlining.