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Survival curves of mice following acute toxoplasmosis in the pretreatment group. BALB/c mice groups (n = 6) were treated with propranolol at 2 or 3 mg/kg/day, pyrimethamine (PYR; 50 mg/kg/day) plus propranolol at 2 or 3 mg/kg/day, pyrimethamine (50 mg/kg/day) (as the positive control), or PBS (as the negative control) 48, 24, and 4 h before challenge with 1 × 103 T. gondii tachyzoites.
