TABLE 1.

Anti-Toxoplasma activity of different doses of propranolol drug in brain and eye tissues in the acute phase (pretreatment group)

Drug	Dose (mg/kg)	Brain		Eye
		CTa (mean parasite load)	P value	CT (mean parasite load)	P value
Propranolol	2	24.50 ± 1.34 (43,172)	<0.001	24.08 ± 1.64 (192,931)	<0.001
		23.13 ± 1.26 (119,020)	<0.001	23.47 ± 1.53 (275,649)	<0.001
Propranolol + pyrimethamine	2 + 50	22.75 ± 4.50 (70,928)	<0.001	26.19 ± 1.27 (4,007)	<0.001
	3 + 50	23.83 ± 1.29 (14,013)	<0.001	28.19 ± 0.87 (33,230)	<0.001
Pyrimethamine (positive control)	50 mg	25.74 ± 2.23 (40,439)	<0.001	27.04 ± 2.09 (38,643)	<0.001
PBS (negative control)		19.64 ± 1.88 (1,018,000)		20.07 ± 1.22 (961,367)

^aC_T values are means ± SD.