TABLE 1.
Peptide amount after 5 and 24 h of incubation with human and P. aeruginosa elastase at 37°C
Peptide designation | Peptide remaininga (%) by elastase type |
|||
---|---|---|---|---|
Human |
P. aeruginosa
|
|||
5 h | 24 h | 5 h | 24 h | |
Esc(1-21) | 0 | 0 | 0 | 0 |
Esc(1-21)-1c | 78 | 13 | 91 | 77 |
LL-37 | 44 | 0 | 0 | 0 |
Peptide amounts were determined by the peak areas of the RP-HPLC relative to those of the control peptide (dissolved in buffer) at 0 min (set as 100%).