Skip to main content
. 2016 Nov 21;60(12):7340–7346. doi: 10.1128/AAC.01427-16

TABLE 1.

Patient demographics of cohorts undergoing sampling on day one of therapy and at steady state

Demographic Value(s)
Day one (n = 35) Steady state (n = 25)
Age (mean ± SD, range; yr) 8.7 ± 4.6 (1–17) 10.5 ± 6.6 (1–17)
Gender (male:female) 22:13 15:10
Weight (mean ± SD, range; kg) 26.9 ± 14.0 (8.8–67.5) 25.4 ± 16.2 (11.2–67.5)
Duration of therapy (mean ± SD, range; days) 11.9 ± 19.4 (1–41) 15.5 ± 11.3 (9.5–41)
Underlying diagnosis (no. of patients)
    Hematopoietic stem cell transplant
        Leukemia 6 5
        Sickle cell disease 1 1
        Aplastic anemia 1 0
    Chemotherapy
        Leukemia 8 5
        Lymphoma 7 5
        Solid tumor 7 4
    HIV 4 4
    Chronic granulomatous disease 1 1
Clinical syndrome (no. of patients)
    Established infection 6 6
    Empirical treatment 29 19
Pathogen (no. of patients)
    Candida albicans 2 2
    Candida parapsilosis 1 1
    Aspergillus fumigatus 3 3
    Cryptosporidium 1 1
Clinical response (no. of patients)
    Success 29 21
    Failure 8 4
    Breakthrough 1 0