TABLE 3.

Bootstrap estimates of the selected pharmacokinetic model

Parameter	Bootstrap		Final model
	Mean estimate	95% CI	Mean estimate	95% CI
Vin (liter)	10.677	10.646–10.87	10.654	10.67–10.87
Vfin (liter)	2.345	2.181–3.023	2.326	2.162–3.01
Kcp (h−1)	0.311	0.127–0.42	0.210	0.108–0.388
Kpc (h−1)	0.057	0.043–0.061	0.057	0.043–0.061
K (h−1)	0.303	0.21–0.355	0.302	0.21–0.351
CL (liter h−1 70 kg−1)	0.675	0.555–0.781	0.670	0.548–0.797