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. 2016 Nov 21;60(12):7431–7435. doi: 10.1128/AAC.01393-16

TABLE 2.

Geometric mean ratio and 90% confidence intervals for pharmacokinetic parameters (PK analysis set)

Parameter Geometric mean ratio (90% confidence interval)
300-mg phase 3 tablet/100-mg i.v. infusion 300-mg slow-dissolution tablet/300-mg phase 3 tablet 300 mg in oral solution/300-mg phase 3 tableta
AUClast (μg · h/ml) 0.98 (0.89, 1.07) 0.96 (0.88, 1.06) 1.13 (1.02, 1.24)
AUC (μg · h/ml) 1.00 (0.93, 1.07) 0.96 (0.90, 1.03) 1.19 (1.11, 1.28)
Cmax (μg/ml) 0.31 (0.27, 0.35) 1.00 (0.88, 1.12) 1.11 (0.98, 1.25)
a

Oral solution administered as 3 100-mg i.v. solution vials.