TABLE 2.
Parameter | Geometric mean ratio (90% confidence interval) |
||
---|---|---|---|
300-mg phase 3 tablet/100-mg i.v. infusion | 300-mg slow-dissolution tablet/300-mg phase 3 tablet | 300 mg in oral solution/300-mg phase 3 tableta | |
AUClast (μg · h/ml) | 0.98 (0.89, 1.07) | 0.96 (0.88, 1.06) | 1.13 (1.02, 1.24) |
AUC∞ (μg · h/ml) | 1.00 (0.93, 1.07) | 0.96 (0.90, 1.03) | 1.19 (1.11, 1.28) |
Cmax (μg/ml) | 0.31 (0.27, 0.35) | 1.00 (0.88, 1.12) | 1.11 (0.98, 1.25) |
Oral solution administered as 3 100-mg i.v. solution vials.