FIG 1.

Lytic activity of ClyR against planktonic S. mutans cells. (A) Time-killing curves of ClyR. The turbidity of S. mutans MT8148 cells treated with different concentrations of ClyR at 37°C for 60 min was monitored by a microplate reader. (B) Dose-dependent lytic activity of ClyR. S. mutans MT8148 cells were treated with different concentrations of ClyR at 37°C for 10 min, and the residual cell numbers were calculated by plating. (C) TEM image of untreated S. mutans MT8148 cells. (D) TEM image of S. mutans MT8148 cells exposed to 50 μg/ml ClyR for 5 min. Bars = 0.5 μm.