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. 2016 Nov 21;60(12):7522–7523. doi: 10.1128/AAC.01775-16

TABLE 1.

Aminoglycoside resistance of specific eis promoter mutants

Strain eis mutation Treka MIC (μg/ml)
Agar proportion MIC (μg/ml)
KAN AMK KAN AMK
Reference
    H37Rv WTb 2.5 0.5 2.5 1
Clinical
    O16 C14T 40 2 40 4
Recombinant
    R001 WT 2.5 0.5 2.5 1
    R101 G10A 20 2 20 2
    R102 G10A 20 2 20 2
    R103 G10A 20 2 20 2
    R201 C12T 10 0.5 10 2
    R202 C12T 10 0.5 10 2
    R203 C12T 10 0.5 10 2
    R301 C14G 2.5 0.5 2.5 1
    R302 C14G 2.5 0.5 2.5 1
    R303 C14G 2.5 0.5 2.5 1
    R401 C14T 40 2 40 4
    R402 C14T 40 2 40 4
    R403 C14T 40 2 40 4
    R501 C15G 5 0.5 5 1
    R502 C15G 5 0.5 5 1
a

Trek, Sensititre MYCO TB; KAN, kanamycin; AMK, amikacin.

b

WT, wild type.