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. 2016 Nov 21;60(12):7527–7529. doi: 10.1128/AAC.01208-16

TABLE 1.

In vitro potency of piperacillin-tazobactam and commercially available antibiotics against each E. coli isolate

E. coli isolate MIC (μg/ml) fora:
TZP Antibiotic
FEP CRO CAZ CIP CST ATM ETP IPM MEM TOB
C2-9 512 0.25 0.125 1 ≥32 0.5 0.25 ≤0.015 0.125 ≤0.06 8
C3-23 ≥2,048 1 ≤0.06 2 1 1 0.5 0.03 0.125 ≤0.06 1
C6-25 2,048 0.5 0.125 1 ≥32 0.5 0.25 0.03 0.25 ≤0.06 2
C7-1 256 0.5 ≤0.06 2 ≤0.015 1 1 0.125 0.25 ≤0.06 2
C10-11 ≥2,048 0.25 ≤0.06 0.5 ≤0.015 1 0.125 ≤0.015 0.25 ≤0.06 1
C11-14 ≥2,048 0.5 0.125 1 ≤0.015 1 0.25 0.06 0.5 ≤0.06 1
C12-1 512 0.25 0.06 0.5 ≤0.015 0.5 0.125 ≤0.015 0.125 ≤0.06 1
C14-26 ≥2,048 8 0.5 4 0.5 0.5 1 2 0.5 0.25 2
C18-6 ≥2,048 0.125 ≤0.06 0.25 0.03 2 ≤0.06 ≤0.015 0.125 ≤0.06 2
C30-5 256 0.125 ≤0.06 0.25 ≤0.015 0.5 0.125 ≤0.015 0.5 ≤0.06 8
C1-6 16 ≤0.06 2 2 0.015 0.5 2 0.03 1 0.06 4
C1-7 4 0.125 ≤0.06 0.5 8 0.5 ≤0.06 ≤0.015 0.25 ≤0.06 4
C1-23 2 ≤0.06 ≤0.06 0.25 ≤0.015 1 ≤0.06 ≤0.015 0.125 ≤0.06 4
C2-5 4 0.125 0.25 0.5 16 0.5 0.5 ≤0.015 0.125 ≤0.06 1
C2-14 2 ≤0.06 0.125 0.25 0.03 8 0.25 ≤0.015 0.125 ≤0.06 2
C2-19 4 ≤0.06 ≤0.06 2 ≤0.015 0.5 2 ≤0.015 0.125 ≤0.06 0.5
C2-27 2 ≤0.06 ≤0.06 0.125 ≤0.015 0.5 ≤0.06 ≤0.015 0.25 ≤0.06 2
C3-2 4 0.125 ≤0.06 0.5 0.06 0.5 0.125 ≤0.015 0.125 ≤0.06 2
a

TZP, piperacillin-tazobactam; FEP, cefepime; CRO, ceftriaxone; CAZ, ceftazidime; CIP, ciprofloxacin; CST, colistin; ATM, aztreonam; ETP, ertapenem; IPM, imipenem; MEM, meropenem; TOB, tobramycin.