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. 2016 Nov 22;11(11):e0167175. doi: 10.1371/journal.pone.0167175

Table 3. Annual seroconversion and seroreversion rate estimates by the superinfection model based on antigen-specific antibodies.

Antigen Survey Site Number of subjects (N = 609) % seropositive (95%CI) * Seroconversion rate (95%CI) Reversion rate (95%CI)
AMA1 Rainy season Dam 134 61.4 (52.7, 69.3) 0.354 (0.180, 0.696) 0.299 (0.128, 0.698)
No Dam 166 64.5 (56.8, 71.4) 0.369 (0.213, 0.639) 0.273 (0.137, 0.541)
Both 300 63.1 (57.4, 68.4) 0.360 (0.236, 0.550) 0.282 (0.165, 0.480)
Dry season Dam 147 53.1 (44.9, 61.0) 0.189 (0.098, 0.365) 0.179 (0.071, 0.451)
No Dam 162 56.5 (48.7, 64.0) 0.224 (0.127, 0.396) 0.194 (0.088, 0.427)
Both 309 54.9 (49.3, 60.4) 0.208 (0.135, 0.321) 0.189 (0.104, 0.344)
CeITOS Rainy season Dam 134 23.5 (17.0, 31.5) 0.040 (0.019, 0.086) 0.064 (0.011, 0.374)
No Dam 166 28.3 (21.9, 35.7) 0.071 (0.035, 0.144) 0.135 (0.047, 0.393)
Both 300 26.2 (21.5, 31.5) 0.055 (0.032, 0.092) 0.099 (0.040, 0.248)
Dry season Dam 147 5.4 (2.7, 10.6) 0.008 (0.001, 0.042) 0.064 (0.001, 3.281)
No Dam 162 6.2 (3.4, 11.2) 0.007 (0.002, 0.031) 0.033 (0.000, 7.559)
Both 309 5.8 (3.7, 9.1) 0.007 (0.002, 0.022) 0.045 (0.002, 1.217)
CSP Rainy season Dam 134 87.1 (80.2, 91.9) 0.500 (0.292, 0.857) 0.121 (0.036, 0.410)
No Dam 166 81.9 (75.3, 87.1) 0.359 (0.237, 0.545) 0.077 (0.025, 0.240)
Both 300 84.2 (79.6, 88.0) 0.414 (0.300, 0.571) 0.094 (0.042, 0.211)
Dry season Dam 147 54.4 (46.3, 62.4) 0.085 (0.052, 0.138) 0.002 (0.000, 3.270)
No Dam 162 49.1 (41.4, 56.8) 0.072 (0.044, 0.118) 0.001 (0.000, 2.630)
Both 309 51.6 (46.0, 57.2) 0.078 (0.055, 0.110) 0.001 (0.000, 6.680)

*For each antigen, a seropositivity cut-off was estimated using combined log10-transformed antibody OD data from both communities over the two survey time points (calculated as the back-transformed log10-mean OD of the negative distribution + log10-three times the standard deviation, Fig 2).