Table 2.

Cox proportional hazards analysis for risk factors associated with local tumor progression after RFA (n = 176)

Factors	Univariate analysis	Multivariate analysis
	P value (HR, 95% CI)	P value (HR, 95% CI)
Age	0.38
HCV antibody positive	0.28
HCV RNA status (SVR)	0.59
HBs antigen positive	0.44
HBc antibody positive	0.47
Platelet counts (×103/μL)	0.67
Serum albumin level (g/dL)	0.46
Serum total bilirubin level (g/dL)	0.65
Prothrombin time (%)	0.77
AFP level (ng/mL)	0.49
AFP‐L3 index >10%	0.002 (5.10, 1.81–14.3)	0.002 (5.10, 1.82–14.3)
DCP level (mAU/mL)	0.54
Tumor size (cm)	0.19
MFI irregular pattern	0.027 (5.38, 1.21–23.8)	0.025 (5.46, 1.23–24.4)

HR, hazard ratio; CI, confidence interval; SVR, sustained viral response; DCP, des‐gamma‐carboxy prothrombin.