Table 2.

Comparison of associated molecular protein in different groups (mean optical density)

Group	HIF‐1α	NF‐κB	VEGF	MMP9	TNF‐α	IL‐1β
ACNU	0.067 ± 0.012	0.046 ± 0.006	0.021 ± 0.004	0.031 ± 0.006	0.076 ± 0.006	0.027 ± 0.001
HBOT	0.016 ± 0.005	0.003 ± 0.001	0.016 ± 0.008	0.005 ± 0.003	0.005 ± 0.003	0.006 ± 0.003
HBOT+ACNU	0.011 ± 0.005	0.001 ± 0.001	0.008 ± 0.003	0.003 ± 0.002	0.003 ± 0.001	0.003 ± 0.005
Control	0.069 ± 0.014	0.05 ± 0.014	0.049 ± 0.018	0.039 ± 0.001	0.0104 ± 0.02	0.03 ± 0.007

The mice were divided into the four groups randomly: control group (untreated), HBOT (only), nimustine (ACNU) (only), HBOT+ACNU (combination), and each group had five mice, as shown in the Material and Methods section.