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. 2016 Oct 5;5(11):3235–3245. doi: 10.1002/cam4.930

Figure 1.

Figure 1

Increased expression of Tim‐1 in PCNSL. (A) (a) Representative immunohistochemical staining patterns of the (i) Tim‐1‐positive and (ii) ‐negative samples, and (iii) IL‐10‐positive and (iv) ‐negative samples (original magnification, ×600). (b) Representative results of the immunohistochemical staining of the serial sections of PCNSL samples (original magnification, ×100). (c) the fluorescent double staining for Tim‐1 and IL‐10 of PCNSL. (B) Pie charts showing IL‐10‐positive rates in the Tim‐1‐positive (left, n = 26) and ‐negative (right, n = 22) samples. (C) Comparison of the gene expression levels of TIM‐1 and IL‐10 between PCNSL (n = 9) and nodal DLBCL (n = 15) samples using microarray datasets available in the NCBI GEO database (accession number: GSE10524). (D) Comparison of the gene expression levels of TIM‐1 and IL‐10 between PCNSL (n = 34), normal brain (n = 23), astrocytoma (n = 26), glioblastoma (n = 81), and oligodendroglioma (n = 50) samples using microarray datasets available in the NCBI GEO database (accession numbers: GSE4290 and GSE34771). DLBCL, diffuse large B‐cell lymphoma.