Figure 5.

Effects of MDPV (1 mg·kg⁻¹, s.c.) on BP (A) and HR (B) alone and after pretreatment with the β₁‐adrenoceptor antagonist atenolol (1.0 and 3.0 mg/kg, s.c.). Dark bars are treatments that are significantly different (P<0.05) from the saline + saline control (Sal + Sal). * P<0.05, significant differences between pretreatment + MDPV compared with MDPV alone;. Each bar is mean ± SEM (n = 7, except for the atenolol 3 + MDPV group that was n = 6 due to the loss of data from one rat) for the first hour of the session.