Table 1.

Newly generated neurons in the hippocampus and subventricular zone after the in vivo expression of reprogramming factors. To identify newly generated cells, mice were injected daily with BrdU up to 12 days. Eight weeks after the treatment, histological evaluations were performed.

Group	Hippocampus			Subventricular zone
	BrdU+	BrdU+ βIII-tubulin+	BrdU+NeuN+	BrdU+	BrdU+Nestin+	BrdU+GFAP+
	(×103 cells/mm3)	(×103 cells/mm3)	(×103 cells/mm3)	(×103 cells/mm3)	(×103 cells/mm3)	(×103 cells/mm3)
GFP	8.1 ± 2.0	3.0 ± 1.6	2.1 ± 1.6	29.6 ± 7.4	3.6 ± 1.5	5.7 ± 2.0
Rep + GFP	17.6 ± 1.9∗	9.2 ± 2.3∗	13.2 ± 5.1∗	57.7 ± 4.1∗∗	15.3 ± 2.6∗∗	16.5 ± 4.8∗
Fold change	2.2	3.1	6.2	2.0	4.3	2.9

BrdU, 5-bromo-2-deoxyuridine; GFP, green fluorescent protein; Rep, reprogramming factors.

  ^∗ p < 0.05, ^∗∗ p < 0.01, and n = 3 per group.