Figure 4.

Effect of NBD on serum cytokine concentrations in mice with ALI. Values are expressed as the mean ± SD (n = 6). Increased serum TNF-α, IL-1β, IL-6, and IL-10 levels were detected in mice in response to LPS or N-NBD + LPS treatment. NBD decreased serum cytokine levels in ALI mice in a dose-dependent manner. A represents versus control group, ^A P < 0.05; B represents versus model group, ^B P < 0.05; C represents versus N-NBD group, ^C P < 0.05; D represents versus NBD-2 group, ^D P < 0.05; E represents versus NBD-6 group, ^E P < 0.05.