Fig. 7.

Hematoxylin and eosin stained proximal caput and distal cauda of epididymis of adult mice under different treatments

Each column shows different treatment groups, viz., control (C), diabetic (D), diabetic-plus-hyperthyroid (DH), and hyperthyroid (H). Normal findings in control were captured at magnifications of 100× and 400× in A1, A3 and A2, A4, respectively. Comparatively, the epididymis of the DH mice was found to be critically damaged, with the caput depicting lack of germ cells in the lumen, broken and weak stereocilia (black arrows), and lipid vacuolization (green arrow heads) in the principal cells in panels C1 and C2 and inflammatory infiltrations (red arrow heads) were noticed in C1. The round bodies and exfoliated germ cells (yellow arrow heads) in C3 and C4, cribriform changes and compaction of clear cells (red arrows) are marked in the cauda epididymis in C4 and D4. Bars are 50 μm in size (Note: for interpretation of the references to color in this figure legend, the reader is referred to the web version of this article)