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. 2016 Nov 26;8(11):384–395. doi: 10.4252/wjsc.v8.i11.384

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©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Network model for CTNNB1 and related genes. A: Network model for CTNNB1 and genes mutated along with CTNNB1. The networks of extracted CTNNB1 with other mutated genes plus that of extracted CTNNB1 alone are shown (cBioPortal-oriented, Stomach Adenocarcinoma)[16]; B: Network model for CTNNB1 and 6 mutated genes. Wnt and LEF/TCF signaling are merged in CTNNB1 signaling (cBioPortal-oriented, Stomach Adenocarcinoma)[16].