Table 3. Genotypic distribution of MBL2 gene polymorphisms included in this meta-analysis.
First author & Ref. no. | Controls | Cases | HWE | ||||||
---|---|---|---|---|---|---|---|---|---|
Combined rs1800450, rs1800451, rs5030737 | Minor allele | Combined rs1800450, rs1800451, rs5030737 | Minor allele | ||||||
AA | AO | OO | MAF | AA | AO | OO | MAF | p-value | |
Garcia et al.14 | 71 | 34 | 1 | 0.16 | 48 | 24 | 4 | 0.21 | 0.156 |
Heidi et al.15 | 108 | 34 | 6 | 0.15 | 92 | 55 | 8 | 0.22 | 0.128 |
Araujo et al.16 | 101 | 56 | 2 | 0.18 | 102 | 62 | 3 | 0.20 | 0.057 |
Capparelli et al.20 | 166 | 112 | 10 | 0.22 | 55 | 158 | 61 | 0.51 | 0.087 |
Alagarasu et al.22 | 86 | 53 | 7 | 0.22 | 212 | 121 | 32 | 0.25 | 0.747 |
Soborg et al.23 | 271 | 131 | 30 | 0.22 | 289 | 132 | 22 | 0.19 | 0.030 |
Garcia et al.25 | 183 | 134 | 27 | 0.27 | 70 | 33 | 3 | 0.18 | 0.721 |
Selvaraj et al.26 | 37 | 18 | 3 | 0.20 | 24 | 19 | 5 | 0.30 | 0.678 |
Soborg et al.28 | 157 | 86 | 7 | 0.20 | 71 | 30 | 8 | 0.21 | 0.235 |
Selvaraj et al.30 | 68 | 39 | 2 | 0.19 | 107 | 73 | 22 | 0.28 | 0.175 |
Genotype rs7096206 | Genotype rs7096206 | ||||||||
YY | YX | XX | YY | YX | XX | ||||
Wu et al.11 | 318 | 120 | 15 | 0.16 | 97 | 47 | 7 | 0.20 | 0.379 |
Chen et al.12 | 296 | 113 | 10 | 0.15 | 325 | 166 | 12 | 0.18 | 0.839 |
Chen et al.13 | 159 | 49 | 8 | 0.15 | 123 | 77 | 5 | 0.21 | 0.097 |
Heidi et al.15 | 110 | 32 | 6 | 0.14 | 101 | 49 | 5 | 0.19 | 0.076 |
Thye et al.18 | 1663 | 486 | 31 | 0.12 | 1437 | 396 | 26 | 0.12 | 0.502 |
Alagarasu et al.22 | 72 | 61 | 13 | 0.29 | 218 | 133 | 14 | 0.22 | 0.987 |
Liu et al.24 | 151 | 54 | 7 | 0.16 | 91 | 44 | 6 | 0.19 | 0.430 |
Genotype rs11003125 | Genotype rs11003125 | ||||||||
HH | HL | LL | HH | HL | LL | ||||
Wu et al.11 | 101 | 248 | 104 | 0.50 | 46 | 64 | 41 | 0.48 | 0.043 |
Heidi et al.15 | 19 | 61 | 68 | 0.66 | 10 | 63 | 82 | 0.73 | 0.366 |
Thye et al.18 | 1878 | 289 | 9 | 0.07 | 1570 | 266 | 7 | 0.07 | 0.550 |
Liu et al.24 | 49 | 105 | 58 | 0.52 | 44 | 66 | 31 | 0.45 | 0.911 |
Genotype rs7095891 | Genotype rs7095891 | ||||||||
PP | PQ | PP | PQ | ||||||
Wu et al.11 | 364 | 87 | 2 | 0.10 | 124 | 26 | 1 | 0.09 | 0.181 |
Thye et al.18 | 825 | 1086 | 319 | 0.38 | 725 | 920 | 308 | 0.39 | 0.204 |
Liu et al.24 | 171 | 39 | 2 | 0.10 | 118 | 22 | 1 | 0.08 | 0.891 |
MAF, Minor allele frequency, HWE, Hardy Weinberg equilibrium.