Table 4.

Effects of intracoronary nitroglycerin on coronary haemodynamics in patients with normal or abnormal endothelial function

	Endothelial function
	Baseline		After nitroglycerin
	Normal	Abnormal	Normal	Abnormal
Heart rate, bpm	71±2	72±2	75±2†	78±2†
Mean arterial pressure, mm Hg	100±2	95±2	95±2†	91±2
Cross-sectional area, mm2	4.6±0.3	4.0±0.3	5.7±0.3†	4.9±0.3†
CBF, ml/min	56.2±4.9	52.0±3.9	59.4±5.1	55.8±4.3
Coronary resistance, mm Hg/ml/min	2.29±0.17	2.41±0.17	2.22±0.17	2.52±0.24
CFR	3.0±0.1	3.1±0.1	3.9±0.2†	3.7±0.2†
APV, cm/s	24.2±1.0	27.6±1.4	21.3±1.5	24.8±1.7
ACC, m/s2	2.3±0.3	2.4±0.2	2.8±0.4	3.9±0.4† ‡
DSVR	1.96±0.07	2.29±0.12‡	4.05±0.45†	6.27±0.97† ‡
WSR, 1/s	440±26	559±41‡	339±29†	457±41* ‡

All values are mean±SE.

^*p<0.05 versus baseline.

^†p<0.01 versus baseline.

^‡p<0.05 versus normal endothelial function.

ACC, acceleration of peak velocity; APV, average peak velocity; CBF, coronary blood flow; CFR, coronary flow reserve; DSVR, diastolic to systolic velocity ratio; WSR, wall shear rate.