Table 2.
Three proposed 7-locus MLST schemas for M. hominis: The three schemas contain variations of 9 genes that confer phylogenetic relationships similar to those found using whole genome SNPs. Schemas B and C show higher marginal diversity in Hunter-Gaston diversity indicex than schema A. Whereas, schema A shows lowest dN/dS ratio among the three
| Gene name | SCHEMA A | SCHEMA B | SCHEMA C | dN/dS (95% CI) | Diversity Index (95% CI) |
|---|---|---|---|---|---|
| MHO_4840a
GENE-20 |
+ | + | + | 0.09(0.08-0.1) | 0.99(0.97-1.00) |
| MHO_0720a
GENE-58 |
+ | + | + | 0.27(0.25-0.29) | 0.97(0.92-1.00) |
|
secD
GENE-94 |
+ | + | + | 0.07(0.05-0.09) | 0.97(0.92-1.00) |
|
oppA
GENE-138 |
+ | + | 0.23(0.21-0.25) | 0.96(0.91-1.00) | |
|
argS
GENE-183 |
+ | + | 0.07(0.05-0.09) | 0.96(0.91-1.00) | |
|
hiss
GENE-236 |
+ | + | 0.09(0.06-0.12) | 0.96(0.96-1.00) | |
| MHO_1160a
GENE-265 |
+ | + | 0.02(0.01-0.03) | 0.97(0.92-1.00) | |
|
tyrS
GENE-428 |
+ | + | 0.01(0.01-0.01) | 0.97(0.92-1.00) | |
|
dnaG
GENE-519 |
+ | + | 0.11(0.09-0.14) | 0.99(0.97-1.00) | |
| Mean dN/dS (95% CI) | 0.1(0.08-0.11) | 0.13(0.11-0.15) | 0.11(0.09-0.13) | ||
| Mean Diversity (95% CI) | 0.97(0.97-0.98) | 0.97(0.96-0.98) | 0.97(0.96-0.98) |
a gene encoding a hypothetical protein. Gene name relates to annotation in ATCC 23114