Table 2.

Distribution of avian influenza virus antigen visualized by immunohistochemical staining in tissues by isolate

Bird ID	Detection of avian influenza virus antigen in tissues
	Nasal epithelium	Nasal glands	Trachea	Lung	Heart	Brain	Liver	Kidney	Adrenal gland	Spleen	Intestine	Pancreas	Harderian gland	Thymus	Bursa	Proventric
A/Northern Pintail/WA/40964/2014
1043	+	+	−	+	++	+++	+	+	+++	+	+	+++	−	−	+	−
1045	+	++	−	+	+	+++	−	−	+++	−	+	+++	++	++	+	−
1047	+	+	−	+	+	+++	+	+	+++	+	+	+++	+	+	++	+
1052	+	++	−	+	−	+++	+	++	++	−	−	+		+	+	−
1053	+	++	−	−	++	+++	+	+	++	−	++	+++	+	+	++	−
1056	++	++	+	++	++	+++	+	++	+++	−	+++	++	+	++	++	+
A/turkey/MN/12528/2015
1093	++	+++	−	+	++	+++	−	+	−	−	−	++	+	+	+	−
1097	+	++	+	+	+++	+++	++	+	++	+	−	++	+++	+	+	+++
A/chicken/IA/13388/2015
1040	+	+	−	+	+++	+++	+	+	+++	+	−	+++	+	−	+	−
1050	+	++	−	+	++	+++	−	+	++	−	−	+++	−	+	++	−

Turkeys were selected for examination because they were presenting with clinical illness at 4 days post challenge (DPC) (A/Northern Pintail/WA/40964/2014) or 3DPC (A/turkey/MN/12528/2015 and A/chicken/IA/13388/2015)

− = no positive cells; + = single positive cells; ++ = scattered groups of positive cells; +++ = widespread staining

Proventric. = proventriculus