Table 1.
Baseline demographics and characteristics
| Patient characteristics | MM patients (n = 7895) | Non-MM patients (n = 23,685) |
|---|---|---|
| Duration of follow-up, years | ||
| Median (range) | 2 (0–9) | 2 (0–10) |
| Age at index date, years | ||
| Mean ± SD | 65.3 ± 11.8 | 65.3 ± 11.8 |
| Median (range) | 64 (18–97) | 64 (18–97) |
| Age, years, n (%) | ||
| 18–34 | 26 (0.3) | 78 (0.3) |
| 35–44 | 239 (3.0) | 717 (3.0) |
| 45–54 | 1130 (14.3) | 3390 (14.3) |
| 55–64 | 2747 (34.8) | 8241 (34.8) |
| 65–74 | 1812 (23.0) | 5436 (23.0) |
| 75+ | 1941 (24.6) | 5823 (24.6) |
| Sex, n (%) | ||
| Male | 4400 (55.7) | 13,200 (55.7) |
| Female | 3495 (44.3) | 10,485 (44.3) |
| Year of index date, n (%) | ||
| 2005 | 634 (8.0) | 1591 (6.7) |
| 2006 | 639 (8.1) | 1464 (6.2) |
| 2007 | 607 (7.7) | 1492 (6.3) |
| 2008 | 892 (11.3) | 2154 (9.1) |
| 2009 | 1136 (14.4) | 3193 (13.5) |
| 2010 | 832 (10.5) | 2445 (10.3) |
| 2011 | 1007 (12.8) | 3644 (15.4) |
| 2012 | 1102 (14.0) | 4177 (17.6) |
| 2013 | 908 (11.5) | 3039 (12.8) |
| 2014 | 138 (1.7) | 486 (2.1) |
| Comorbidities at baseline, n (%) | ||
| Hypertension | 3002 (38.0) | 5750 (24.3) |
| Renal failure | 1698 (21.5) | 696 (2.9) |
| Hyperlipidemia | 1399 (17.7) | 3712 (15.7) |
| Diabetes mellitus | 1242 (15.7) | 3007 (12.7) |
| Ischemic heart disease | 841 (10.7) | 1777 (7.5) |
| Cardiac dysrhythmias | 563 (7.1) | 1019 (4.3) |
| Congestive heart failure | 526 (6.7) | 549 (2.3) |
| Cardiomyopathy | 168 (2.1) | 176 (0.7) |
| Amyloidosis | 110 (1.4) | 3 (0.01) |
| Acute myocardial infarction | 106 (1.3) | 133 (0.6) |
| Cerebrovascular diseasea | 100 (1.3) | 159 (0.7) |
| Hypertension + renal failure | 1034 (13.1) | 494 (2.1) |
| Hypertension + congestive heart failure | 322 (4.1) | 320 (1.4) |
| Hypertension + renal failure + congestive heart failure | 179 (2.3) | 116 (0.5) |
| CCI | ||
| Mean ± SD | 1.44 ± 1.93 | 0.41 ± 1.01 |
| Median (range) | 1 (0–12) | 0 (0–15) |
CCI: Charlson comorbidity index, MM: multiple myeloma, SD: standard deviation
aBased on inpatient claim only