Table 2.

Multivariable Cox proportional hazards model: Predictors of hypertension

Predictor	Level	HR (95% CI)	p-value
Patient cohort (reference: non-MM patients)	MM patients	1.30 (1.22, 1.37)	<0.0001
Age (reference: 18–54 years)	55–64 years	1.82 (1.69, 1.97)	<0.0001
	65–74 years	2.55 (2.36, 2.76)	<0.0001
	75+ years	2.88 (2.66, 3.11)	<0.0001
Comorbidities at baseline (yes vs. no)	Ischemic heart disease	1.29 (1.20, 1.40)	<0.0001
	Renal failure	1.43 (1.27, 1.61)	<0.0001
	Diabetes mellitus	1.72 (1.59, 1.86)	<0.0001
	Hyperlipidemia	1.16 (1.07,1.26)	<0.0001
CCI (reference: low [0])	Mild (1,2)	1.11 (1.03, 1.20)	<0.01

CCI Charlson comorbidity index, HR hazard ratio, MM multiple myeloma