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Molecular and genetic markers
| LTS group | Control group | P value | |
|---|---|---|---|
|
IDH1 (immunohistochemistry) |
6/40 | 1/34 | 0.043 |
| IDH1 (genetic) | 6/38 | 1/33 | 0.043 |
| IDH2 (genetic) | 0/38 | 0/33 | n.s. |
| 1p/19q | 0/38 | 1/34 | n.s. |
| 1p | 3/38 | 1/34 | n.s. |
| 19q | 10/38 | 6/34 | n.s. |
| MGMT methylation | 36/38 | 12/33 | < 0.001 |
| CDKN2A (deletion) | 29/39 | 25/34 | n.s. |
| CDKN2B (deletion) | 27/39 | 24/34 | n.s. |
IDH = izocitratedehidrogenaze; LTS = long term survivor; MGMT = methyl guanine methyl transferase; n.s. = non-significant
