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. Author manuscript; available in PMC: 2017 Jul 12.
Published in final edited form as: Circulation. 2016 Jun 30;134(2):153–167. doi: 10.1161/CIRCULATIONAHA.116.022304

Figure 3.

Figure 3

β2ARKO mice have splenomegaly and retention of leukocyte populations. (A) Representative images of spleens from WT and β2ARKO BMT animals. (B) Gravimetric analysis of spleen weight to body weight (SW/BW) of spleens from WT and β2ARKO BMT sham and MI animals. n=6 for WT BMT sham, n=8 for β2ARKO BMT sham, n=4 for WT BMT 1d, n=4 for β2ARKO BMT 1d, n=10 for WT BMT 4d, n=7 for β2ARKO BMT 4d, n=7 for WT BMT 7d, n=5 for β2ARKO BMT 7d. Exact Wilcoxon rank-sum tests, * p < 0.05, ‡ p < 0.001 vs WT BMT. (C) Representative CD68, tryptase and MPO staining from 4d post-MI spleens of WT or β2ARKO BMT mice. (D) Quantification of CD68, tryptase and MPO staining from WT and β2ARKO BMT spleens 4d following MI surgery. n=10 for WT BMT, n=8 for β2ARKO BMT, Exact Wilcoxon rank-sum tests, * p < 0.05, ‡ p < 0.001 vs WT BMT.