Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Targeted biotinylation of telomeres, major and minor satellites. Representative confocal images of C2C12 cells, co-transfected with CAG-BirA*-dCas9-eGFP and a plasmid encoding either telomere- (A, TelgRNA), minor satellite- (B, MiSgRNA) or major satellite-specific sgRNA (C, MaSgRNA). Nuclear enrichment of biotin at targeted sequences is only detectable after addition of exogenous biotin. White dashed lines indicate the border between nucleus and cytoplasm. Scale bar: 10 µm.
