Table I.
Consensus regions of genomic imbalance in five EC cell lines.
| Cytogenetic location | Genes |
|---|---|
| Regions of gain | |
| 2q37.1 | NCL |
| 3p21.31 | DHX30 |
| 3p24 | TOP2B |
| 3q29 | ATP13A3, DLG1, GP5 |
| 5q23.2 | C5orf48, RNUXA |
| 5q23.3-q31.1 | LMNB1 |
| 5q31 | ALDH7A1, BRD8, C5orf5, CDC23, CDC25C, FAM53C, KDM3B, KIF20A, NME5, REEP2, TAF7, WNT8A, ERD8 |
| 5q31.1-q31.3 | EGR1, ETF1, HSPA9, GFRA3 |
| 5q32 | LARS |
| 7p15 | HNRNPA2B1 |
| 17q12-q23.2 | CDC27 |
| 17q21-q22 | TOP2A |
| 17q25 | FASN |
| 19pter-q12 | EEF2 |
| 19q13 | SLC17A7 |
| 19q13.1-q13.4 | SLC6A16 |
| 19q13.3 | FCGRT, BCL2L12, CD37, FCGRT, FLT3LG, HRC, KCNA7, LIN7B, PRMT1, RPL13A, RPS11, RUVBL2, SNRP70, TEAD2 |
| 19q13.32 | CGB1, CGB |
| 19q13.33 | PRR12, ALDH16A1, CPT1C, CCDC155, NOSIP, PIH1D1, PPFIA3, PRRG2, RCN3, PTH2, TRPM4, AK097351, DKKL1 |
| 19q13.3-q13. | IRF3 |
| 19q13.3-q13.4 | SCAF1 |
| 19q13.3-qter | RRAS |
| chr19 | AK126060 |
| Regions of loss | |
| 3p12.3 | ZNF717 |
| 3p14.1 | LOC285300 |
| 10p11.1 | HSD17B7P2, CDC10L, LOC100129055, ZNF25 |
| 10p11.2 | ZNF33A, ZNF37A |
| 10p11.21 | ANKRD30A, ZNF248 |
| 10q11.1 | LOC283027 |
| 10q11.2 | ZNF33B, ZNF37B, LOC728064, LOC84856, CCNYL2, BMS1 |
| 11p11.12 | LOC441601, LOC440040, LOC646813 |
| 11p11.12-q12 | TRIM49 |
| 11p11.2 | FOLH1 |
| 11q11 | OR5G5P, OR4A16, TRIM48 |
| 11q12.1 | OR9Q1 |
| 11q23.1-23.2 | NNMT, CADM1, LOC283143 |
| 14q31 | NRXN3 |
| 15q25 | NTRK3, NCRNA00052 |
| 18p11 | ANKRD30B, ANKRD20A5, FLJ44255, CXADRP3, POTEC, ZNF519 |
| 21q11.2 | C21orf99 |
| chr3 | BC019327 |
| chr10 | AL833559, BC035410 |
| chr11 | AB231735, AK096987 |
| chr15 | AL109696 |