(A) T1-Gad MRI and co-registered MRI/AMT-PET fusion images of patient #2 showing a left medial fronto-parietal contrast-enhancing lesion (arrows) suspicious for glioblastoma recurrence 4 months after initial treatment. High AMT uptake was seen in the same region (upper panel), extending superior (and also inferior and lateral) to the contrast-enhancing lesion (lower panel), with an SUVmax of 4.7. After MRI progression, 1 month later, the Gad+ mass grew into and filled the original PET+/Gad− area.
(B) T1-Gad MRI and co-registered MRI/AMT-PET fusion images of patient #11 showing a left parieto-occipital contrast-enhancing lesion. The PET+ area was almost congruent with the bulk of the Gad+ lesion, which showed no progression during the 2-year follow-up. SUVmax was below 4 (3.8).