Table 2. Severity of histological lesions in samples of EBOV challenged animals after treatment (second efficacy study).

	Lesion	Placebo			NB-DNJ						Untreated
		1	2	3	4	5	6	7	8	9	10	11	12
Liver	Hepatocyte vacuolation	Mod	WNL	Min	Mkd	Mkd	WNL	Min	WNL	Mkd	Mild	Mkd	Mild
	Focal necrosis	Mild	Min	Mild	WNL	Min	Min	Min	Mod	Mod	Mod	Mod	Mkd
	Focal mineralisation	Min	Mod	WNL	WNL	WNL	WNL	WNL	WNL	WNL	WNL	Mod	WNL
Splenic red pulp	Congestion	Mod	Min	Mod	Mod	Mod	Mild	Mod	Mild	Mild	Mod	Min	Mild
	Scattered single cell necrosis	Mod	WNL	Mod	Mod	Mild	Mod	Mild	Mod	Min	WNL	Min	Min
	Patchy polymorph infiltration	Min	Mod	Min	Mild	Min	Mod	Mod	Min	Min	WNL	Min	Min
Splenic white pulp	Scattered single cell necrosis	Min	WNL	Mod	Mild	Mild	Mild	Min	Min	WNL	Min	Min	Min
	Lymphocyte depletion	Mild	Mild	Mild	Mild	Mild	Mild	Min	WNL	Mod	WNL	Min	WNL

WNL (within normal limits, dark blue) and Min (minimal, light blue), Mild (white), Mod (moderate, pink) and Mkd (marked, red). Guinea pig 2 survived until day 14.