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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: Behav Brain Res. 2016 Jun 14;312:163–168. doi: 10.1016/j.bbr.2016.06.019

Fig. 3.

Fig. 3

Estrogen facilitates the antinociceptive effect produced by 250 nmol pentazocine in normally cycling females. Pentazocine significantly increased the TFL from 5 to 50 minutes in only proestrous females, but not in diestrous animals. Number of animals per group: proestrous-pentazocine=3, diestrous-pentazocine=3, proestrous-vehicle=3, diestrous-vehicle=5.