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Pretreatment with CTAP increased the duration of the antinociceptive effect of 500 nmol pentazocine in OVX+E rats. The antinociceptive effect of 500 nmol pentazocine was mediated by KOR. Number of animals per group: pentazocine=6, pentazocine+CTAP=6, pentazocine+nor-BNI=6, vehicle+CTAP=3, vehicle+nor-BNI=3.
