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. Author manuscript; available in PMC: 2016 Nov 23.
Published in final edited form as: J Proteomics. 2013 Apr 30;90:14–27. doi: 10.1016/j.jprot.2013.04.026

Fig. 3.

Fig. 3

Validation of proteomic data for the proteins flotillin-1, sarcosynapsin, supervillin, versican core protein and FHL1 by immunolocalization studies performed on skeletal muscle section of desminopathy patients. Abnormal muscle fibers were detected by immunostaining with primary antibodies against myotilin (B, E, H, K, N). Corresponding to the results of proteomic analysis, abnormal fibers show an increased immunoreactivity for flotillin-1 (A), sarcosynapsin (D), supervillin (G), versican core protein (J) and FHL1 (M). C, F, I, L, O: merged images. Scale bar = 25 µm.