Table 1.
Aerosol challenge doses of M. tuberculosis delivered to rhesus macaques.
| Group | Vaccine and route | Animal Identification number | Presented Dose (cfu) | Estimated Retained Dose (cfu) |
|---|---|---|---|---|
| Group A | BCG ID | S6 | 571 | 82 |
| S14 | 535 | 76 | ||
| S17 | 666 | 95 | ||
| S22 | 632 | 90 | ||
| S26 | 1215 | 174 | ||
| S43 | 627 | 90 | ||
| Group B | BCG ID + IT | S12 | 647 | 92 |
| S24 | 714 | 102 | ||
| S42 | 773 | 111 | ||
| S45 | 525 | 75 | ||
| S58 | 535 | 76 | ||
| S63 | 802 | 115 | ||
| Group C | BCG IV | S4 | 688 | 98 |
| S7 | 812 | 116 | ||
| S19 | 744 | 106 | ||
| S20 | 447 | 64 | ||
| S35 | 1016 | 145 | ||
| S61 | 802 | 115 | ||
| Group D | No vaccine | S23 | 515 | 74 |
| S33 | 525 | 79 | ||
| S36 | 1176 | 168 | ||
| S40 | 972 | 139 | ||
| S51 | 622 | 89 | ||
| S50 | 539 | 77 | ||
| Study median | 657 | 94 |
Route of delivery: ID: intradermal; IV: intravenous; IT: intratracheal.