Table 3.
Estimated rates of fatal stroke and incident stroke per 100,000 per year (95% CI) adjusted for age group (45-64, 65-74, 75+), race, sex and the age group x race interaction; and hazard ratios compared to low-mortality counties (Quartile 1) (95% CI) similarly adjusted; and number of fatal strokes (death within 30-days of incident stroke) and total incident stroke events; percentages of fatal stroke events, and 95% confidence intervals for the percentages of fatal strokes; and odds ratios and 95% CIs (relative to the low mortality counties, Quartile 1) for fatal stroke after adjustment for age group (45-64, 65-74, 75+), race, and sex. Quartiles calculated from U.S. vital statistics, 2005-2007 and 2008-2010.10,11 Proportional hazards estimated with age as a continuous factor. P-trend estimated from the proportional hazards model.
| County-Level Stroke Mortality Quartile | Fatal Strokes | Incident Stroke (fatal or nonfatal) | Case Fatality | |||
|---|---|---|---|---|---|---|
| Rate/100,000 (95% CI) | Hazard Ratio (95% CI) | Rate/100,000 (95% CI) | Hazard Ratio (95% CI) | # Fatal / # Strokes % (95% CI) | Odds Ratio (95% CI) | |
| Quartile 1 | 90 (67 – 121) | 1.00 (ref) | 658 (588 – 735) | 1.00 (ref) | 46/279 16.5% (12.3% - 21.4%) |
1.0 (ref) |
| Quartile 2 | 140 (110 – 178) | 1.55 (1.06 – 2.25) | 690 (618 – 771) | 1.06 (0.90 – 1.25) | 68/284 23.9% (19.0% - 29.3%) |
1.66 (1.08 - 2.53) |
| Quartile 3 | 109 (82 – 144) | 1.21 (0.81 – 1.81) | 701 (627 – 784) | 1.09 (0.92 – 1.29) | 51/281 18.2% (13.8% - 23.2%) |
1.18 (0.76 – 1.85) |
| Quartile 4 | 174 (138 – 218) | 1.95 (1.35 – 2.81) | 844 (761 – 937) | 1.29 (1.10 – 1.52) | 77/323 23.8% (19.3% - 28.9%) |
1.71 (1.13 – 2.59) |
| p-trend | 0.0025 | 0.0023 | 0.058 | |||