Table 1.

Examples of drugs targeted at GPCRs.

Name	Disease	Receptor and mode of action
Claritin, Allegra	allergies	H1 antagonist
Zyprexa	schizophrenia	D1, D2, 5-HT2 antagonist
Risperdal	psychosis	D2, 5-HT2A antagonist
Imigran	migraine	5-HT1 agonist
Buspar	depression	5-HT1a agonist
Cozaar, Diovan	hypertension	AT1 antagonist
Lupron a, Zoladex a	cancer	LH-RH agonist
Neurontin	neurogenic pain	GABA B agonist
Serevent	asthma	β2 agonist
Plavix	stroke	P2Y12 antagonist
Zantac, Pepcidine	ulcers	H2 antagonist
Oxytocin a	uterus contraction	OTR agonist
Insulin a	diabetes	IR agonist

^aPeptides