Independent predictors of transfusion. Multivariable logistic regression analysis identified several parameters. The strongest predictor was severe anemia with hematocrit level below 30% followed by congestive heart failure, dependent function status, preoperative coagulopathy and creatinine elevation > 1.2 mg/dl. Intriguingly, BMI > 30 kg/m2 was protective. These data were the basis for the development of a risk prediction model with a c-statistic for discrimination of 0.81. Model score points are shown for each predictor.