. Author manuscript; available in PMC: 2017 Dec 1.

Published in final edited form as: Ophthalmology. 2016 Oct 1;123(12):2527–2536. doi: 10.1016/j.ophtha.2016.08.036

Table 4.

Cox Proportional Hazards Analysis.

	Hazards Ratio	95% confidence interval	p-value
Age (decade)	1.40	1.14 – 1.71	0.0011
Gender (male)	1.53	1.05 – 2.23	0.025
IOP (per 2.7 mm Hg [SE])	1.28	1.03 – 1.46	0.021
CCT (per 37 microns [SE])	1.57	1.30 – 1.89	0.0000028
Vertical cup-to-disc ratio (per 0.19 [SE])	1.62	1.33 – 1.96	0.00000096
Visual Field defect (PSD, per 0.25 [SE])	1.20	0.99 – 1.45	0.070
TMCO1 (per risk allele)	1.73	1.28 – 2.34	0.00036

The OHTS risk calculator was adapted to include number of TMCO1 risk alleles. Hazards ratios were normalized by standard error (SE).