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. 2016 Nov 24;7:578. doi: 10.3389/fphys.2016.00578

Figure 4.

Figure 4

Effects of EPA in membrane cholesterol-depleted cells with methyl-β-cyclodextrin (MβCD). (A) Current records obtained from the same cell and generated by KV7.1-KCNE1 channels in control, after perfusion with MβCD, with EPA and after washout the cells with EPA-free external solution. (B) Current-voltage relationships under all conditions shown in (A). (C) Plot showing the voltage dependence of the MβCD and EPA effects (D) Activation curves and (E) normalized activation curves. Moreno et al. (2015).