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Renal biochemical and histological analysis of wild-type and Npc1 mutant mice treated with a toxic dose of HPBCD.
Serum creatinine levels (A) and representative renal sections (periodic acid-Schiff stained) (B) 8 h after saline or HPBCD (20,000 mg/kg) subcutaneous injection. Values are the mean ± S.E.M., (n = 5–7). * P < 0.05; n.s., not significant. Scale bar = 400 μm.
