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Pulmonary histological analysis of wild-type and Npc1 mutant mice treated with a toxic dose of HPBCD.
Representative lung sections (hematoxylin eosin stained) (A) and lung injury scores (B) 8 h after saline or HPBCD (20,000 mg/kg) subcutaneous injection. Lung injury score was measured as described in the Material and Methods. Values are the mean ± S.E.M., (n = 5–7). * P < 0.05, ** P < 0.01; n.s., not significant. Scale bar = 400 μm.
