Fig. 4.

Immunohistochemical staining for complex IV MTCO1 in paraffin-embedded liver tissues.

Immunostaining of complex IV in the liver of patient 1 (A, C) and patient 2 (B, D), visualized with permanent red (pink), nuclei were counterstained with hematoxylin (blue). Liver of patient 1 displays a mosaic staining pattern (left panels), while normal staining is observed in patient 2 (right panels). Scale bars = 200 μm (A–B) 50 μm (C–D).