ROC analysis of the inhibition zone diameters of cefoxitin and moxalactam as markers for mecA and mecC gene positivity in Staphylococcus spp. Cefoxitin and moxalactam ROC curves were compared in the following contexts: mecA detection in S. aureus, S. lugdunensis, and S. saprophyticus (A); mecA detection in other staphylococci (B); mecC detection in S. aureus (C); and mecA versus mecC discrimination in S. aureus (D). P values comparing ROC curves were computed using Delong's method. Optimal diameter breakpoints for cefoxitin and moxalactam are indicated by plain and dotted arrows, respectively. Axes of A, B, and C were clipped to 90%, 90%, and 80%, respectively.