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. 2016 Nov 23;54(12):3034–3042. doi: 10.1128/JCM.01193-16

TABLE 4.

Performance comparison of the nine assays in T. gondii-specific IgM antibody detection on routine panelsa and concordance between positive IgM detection and confirmation by the reference method (ISAGA-M) in chronic (>1 year) toxoplasmosis patientsb

Assay Performance (%)
Sensitivityc Specificityd PPV NPV Concordance with ISAGA-M
AdviaCentaure 89.4 98.1 85.7 98.6 81
Architecte 80.9 99.7 97.4 97.6 95.2
AxSYMf 86 100 100 97.9 60
Elecsyse 76.6 96.7 75 97 92.9
Enzygnoste 84.2 99.7 97 98.4 16.7
Liaisone 61.7 98.4 82.4 95.3 59.5
Plateliae 97.9 92.6 63 99.7 97.6
VIDASf 65 99.7 90.5 94.9 70
VIDIAf 79 97.9 90.5 94.3 60
a

Panels containing 419 serum samples in assessment 1 and 406 serum samples in assessment 2.

b

Panels containing 19 serum samples in assessment 1 and 45 serum samples in assessment 2.

c

Sensitivity = true positive/(true positive + false negative).

d

Specificity = true negative/(true negative + false positive).

e

Assessment 2.

f

Assessment 1.