Table 2. Adjusted incidence rate and hazard ratio with 95% confidence interval for gastric cancer according to the combination of Helicobacter pylori antibody and serum pepsinogen.

	Group
	A	B	C+D
Subjects, n	606	1126	714
Cases, n	5	48	70
Age- and sex-adjusted incidence rate, /1000 person-years	0.6	2.4	6.7
Age- and sex-adjusted HR, 95% CI	1.00	4.43 (1.76–11.14)a	11.6 (4.68–28.87)a
Multivariable-adjusted HR, 95% CI	1.00	4.08 (1.62–10.28)a	11.1 (4.45–27.46)a

HR, hazard ratio; CI, confidence interval.

Multivariable-adjustment was made for age, sex, body mass index, total cholesterol, hemoglobin A1c, smoking habits, and daily total energy and salt intake. Groups A to D, see text for details.

^aP < 0.01 vs Group A.