Table 3.
Cox‐Proportional Hazard Model for Predictors of Cardiovascular Death, Myocardial Infarction, or Stroke
| Variable | Adjusted HR (95% CI) | χ2 | P‐Value |
|---|---|---|---|
| Age, per 1‐y increase | 1.035 (1.031–1.039) | 284.3 | <0.001 |
| Congestive heart failure, yes vs no | 1.75 (1.62–1.89) | 191.1 | <0.001 |
| Polyvascular disease vs single vascular disease | 1.52 (1.41–1.64) | 118.5 | <0.001 |
| History of diabetes mellitus, yes vs no | 1.44 (1.34–1.56) | 100.6 | <0.001 |
| Ischemic event ≤1 y vs no ischemic event | 1.67 (1.50–1.85) | 87.7 | <0.001 |
| Ischemic event >1 y vs no ischemic event | 1.48 (1.36–1.61) | 85.6 | <0.001 |
| Statins, yes vs no | 0.74 (0.68–0.80) | 57.0 | <0.001 |
| Japan vs other regions | 0.61 (0.53–0.72) | 39.6 | <0.001 |
| Current smoker vs former or never | 1.37 (1.24–1.52) | 35.9 | <0.001 |
| Eastern Europe and Middle East vs other regions | 1.27 (1.16–1.40) | 23.1 | <0.001 |
| Atrial fibrillation/flutter, yes vs no | 1.24 (1.13–1.36) | 19.4 | <0.001 |
| Sex, male vs female | 1.12 (1.03–1.21) | 7.7 | 0.005 |
| BMI <20, yes vs no | 1.28 (1.06–1.54) | 6.8 | 0.009 |
| Aspirin, yes vs no | 0.93 (0.86–1.01) | 3.0 | 0.08 |
| History of stable angina vs no history of stable angina | 1.06 (0.99–1.14) | 2.6 | 0.11 |
BMI indicates body mass index; HR indicates hazard ratio.