Table 1.
Baseline Community Cohort Characteristics by Sex
| Variable | Total (n=416) | Men (n=288) | Women (n=128) | P Value |
|---|---|---|---|---|
| Age, y | 35±21 | 36±21 | 34±21 | 0.37 |
| Weighted Charlson index | 0.45±1 | 0.52±1.1 | 0.31±0.7 | 0.17 |
| Hypertension, n (%) | 93 (22) | 58 (20) | 35 (27) | 0.10 |
| Smoking, n (%) | 132 (32) | 95 (33) | 37 (29) | 0.40 |
| Diabetes mellitus, n (%) | 15 (4) | 11 (4) | 4 (3) | 0.76 |
| Atherosclerosis, n (%)a | 21 (5) | 15 (5) | 6 (5) | 0.83 |
| Coarctation, n (%) | 30 (7) | 18 (6) | 12 (9) | 0.26 |
| Endocarditis, n (%) | 2 (0.5) | 2 (0.7) | 0 (0) | 0.85 |
| Congenital heart disease, n (%) | 54 (13) | 34 (12) | 20 (16) | 0.29 |
| LV EDD, mm | 50±11 | 51±11 | 48±11 | 0.01 |
| LV ejection fraction, % | 62±7 | 62±8 | 63±7 | 0.22 |
| Aorta diameter, mm | 34±9 | 35±9 | 31±7 | <0.0001 |
| Aorta diameter/heightb, mm/m | 22.5±13 | 22.5±11 | 22.6±17 | 0.94 |
| Aneurysm ≥45 mm, n (%) | 32 (8) | 29 (10) | 3 (2) | 0.002 |
| R‐L cusp fusion BAV, n (%) | 350 (84) | 243 (85) | 107 (84) | 0.88 |
| Any AR, n (%) | 247 (59) | 185 (64) | 62 (48) | 0.003 |
| AR 3+ or 4+, n (%) | 34 (8) | 31 (11) | 3 (2) | 0.003 |
| Any AS, n (%) | 94 (23) | 66 (23) | 28 (22) | 0.89 |
AR indicates aortic regurgitation; AS, aortic stenosis; BAV, bicuspid aortic valve; BSA, body surface area; EDD, end‐diastolic diameter; LV, left ventricle; R‐L, right‐left.
a
History of stroke, transient ischemic attack, and/or myocardial infarction at baseline.
b
Height in meters available for 257 men and 111 women.