Table 2.
Follow‐Up Community Cohort Outcomes by Sex
| Outcome During Follow‐Up | Entire Cohort (n=416) | Men (n=288) | Women (n=128) | P Value |
|---|---|---|---|---|
| AVR, n (%) | 133 (32) | 103 (36) | 30 (23) | 0.01 |
| Severe AS, n (%)a | 84 (20) | 59 (21) | 25 (20) | 0.89 |
| 84/133 (63) | 59/103 (57) | 25/30 (83) | 0.009 | |
| Severe AR, n (%)a | 38 (9) | 34 (12) | 4 (3) | 0.003 |
| 38/133 (28) | 34/103 (33) | 4/30 (13) | 0.04 | |
| Aortic dissection, n (%) | 2 (0.5) | 2 (0.7) | 0 (0) | 0.52 |
| Aorta diameter, mmb | 39±7 (n=336) | 40±7 (n=239) | 37±6 (n=97) | 0.0002 |
| Aneurysm formation, n (%)c | 49 (13) (n=384) | 38 (15) (n=259) | 11 (9) (n=125) | 0.14 |
| Aorta surgery, n (%)d | 49 (12) | 37 (13) | 12 (9) | 0.4 |
| Endocarditis, n (%) | 9 (2) | 9 (4) | 0 (0) | 0.06 |
| Total events, n % | 161 (39) | 123 (43) | 38 (30) | 0.01 |
AR indicates aortic regurgitation; AS, aortic stenosis; AVR, aortic valve replacement; BAV, bicuspid aortic valve.
a
Total (first row) and as cause for aortic valve replacement (second row).
b
There were 336 follow‐up echocardiograms (81%) with aortic diameter measurements in 416 patients.
c
After excluding 32 patients with aneurysms at baseline, the remaining 384 (men 259, women 125) patients remained at risk for aneurysm formation at follow‐up.
d
Surgery for aneurysm, coarctation, or dissection.