Table 6.
STS Surgical Referral Cohort Clinical and Echocardiographic Features by sex
| Variable | Total (N=2242) | Men (N=1663) | Women (N=579) | P Value |
|---|---|---|---|---|
| Age, y | 62±14 | 62±13 | 63±14 | 0.12 |
| NYHA class III or IV, n (%) | 1099 (49) | 764 (46) | 335 (58) | <0.0001 |
| Weighted Charlson index | 1.43±1.7 | 1.48±1.7 | 1.28±1.6 | 0.01 |
| Ejection fraction, % | 59±14 | 58±14 | 62±12 | <0.0001 |
| Preop AS, n (%) | 1969 (88) | 1420 (86) | 549 (95) | <0.0001 |
| Preop severe AR, n (%) | 438 (20) | 383 (23) | 55 (10) | <0.0001 |
| Prosthesis size | 25±2.5 | 25±2.2 | 22±1.8 | <0.0001 |
| Mechanical valve | 1071 (48) | 822 (49) | 249 (43) | 0.009 |
| Coarctation, n (%) | 20 (0.9) | 14 (0.8) | 6 (1) | 0.67 |
| Aorta diameter, mma | 41±9 (n=1679) | 42±7 (n=1236) | 38±12 (n=443) | <0.0001 |
| Aorta diameter/height, mm/ma | 24±5 | 24±4 | 24±7 | 0.71 |
| Aorta cross‐sectional area by height, cm2/ma | 7.8±2.8 | 8.1±2.8 | 7.3±2.9 | <0.0001 |
| Aneurysm (≥45 mm), n (%)a | 484 (22) | 404 (24) | 80 (14) | <0.0001 |
| Concomitant ascending aorta repair, n (%) | 546 (24) | 441 (27) | 105 (18) | <0.0001 |
| Concomitant CABG, n (%) | 612 (27) | 509 (31) | 103 (18) | <0.0001 |
| Indication endocarditis | 49 (2) | 45 (3) | 4 (0.7) | 0.001 |
| ESD for AR ≥2+, mmb | 41±9 (n=234) | 42±9 (n=202) | 35±9 (n=32) | <0.0001 |
| ESD/BSA for AR ≥2+, mm/m2 b | 20±4 | 20±4 | 20±4 | 0.75 |
AR indicates aortic regurgitation; AS, aortic stenosis; CABG, coronary artery bypass surgery; ESD, end‐systolic diameter; NYHA, New York Heart Association class; Preop, preoperative.
a
Aorta diameter by echocardiogram was available for 1679 (75%) (1236 men, 443 women) of 2242 patients; thus, aneurysm % are based on those denominators. Height in meters.
b
ESD diameter was available for 234 (56%) (202 men, 32 women) of 418 patients with AR ≥2+ defined by echocardiogram; thus, ESD/BSA are based on those denominators.